Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients

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This randomized controlled trial evaluates the efficacy of disulfiram and cognitive behavior therapy (CBT) versus interpersonal psychotherapy (IPT) in reducing cocaine use among 121 outpatient participants with cocaine dependence. The study compares four treatment conditions: disulfiram plus CBT, disulfiram plus IPT, placebo plus CBT, and placebo plus IPT, using self-reported data and urine toxicology screens as outcome measures. Results indicate that both disulfiram and CBT significantly reduced cocaine use compared to their respective controls, with benefits being more pronounced for individuals not dependent on alcohol at baseline.

ID
37f8741371ab4e48
Source org
OpenAlex
Author
Kathleen M. Carroll (Yale University), Lisa R. Fenton, Samuel A. Ball, Charla Nich, Tami Frankforter, Julia Shi, Bruce J. Rounsaville
Published
2004-03-01
OA status
bronze
DOI
10.1001/archpsyc.61.3.264
PMID
Not recorded
PMCID
Not recorded
Citations
418

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BibTeX

@article{allodium:37f8741371ab4e48,
  title = {Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients},
  author = {Kathleen M. Carroll and Lisa R. Fenton and Samuel A. Ball and Charla Nich and Tami Frankforter and Julia Shi and Bruce J. Rounsaville},
  year = {2004},
  journal = {OpenAlex},
  doi = {10.1001/archpsyc.61.3.264},
  url = {https://doi.org/10.1001/archpsyc.61.3.264}
}

RIS

TY  - JOUR
TI  - Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients
AU  - Carroll, Kathleen M.
AU  - Fenton, Lisa R.
AU  - Ball, Samuel A.
AU  - Nich, Charla
AU  - Frankforter, Tami
AU  - Shi, Julia
AU  - Rounsaville, Bruce J.
PY  - 2004
PB  - OpenAlex
DO  - 10.1001/archpsyc.61.3.264
UR  - https://doi.org/10.1001/archpsyc.61.3.264
ER  -

APA

Carroll, K. M., Fenton, L. R., Ball, S. A., Nich, C., Frankforter, T., Shi, J., & Rounsaville, B. J. (2004). Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients. OpenAlex. https://doi.org/10.1001/archpsyc.61.3.264

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