Blended Cognitive Behavioral Therapy versus Standard Cognitive Behavioral Therapy for Unipolar Depression: A Multicenter Randomized Controlled Trial

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This multicenter randomized controlled trial compares blended cognitive behavioral therapy (bCBT) using the elona therapy app against standard face-to-face CBT for unipolar depression in 283 German outpatients. The study assesses depressive and anxiety symptoms, quality of life, self-efficacy, and disease severity at baseline and after 12 weeks. Results indicate that patients receiving bCBT showed greater improvements across these primary and secondary outcomes compared to those receiving standard CBT alone.

ID
6920137d7b814b8e
Source org
PubMed Central
Author
Jan Kalde (Heinrich Heine University Düsseldorf), Ece Atik (University of Göttingen), Johannes Stricker (Heinrich Heine University Düsseldorf), Magnus Schückes (University of Mannheim), Peter Neudeck (Chemnitz University of Technology), Pamela Abel (Medizinische Akademie Erfurt), Johanna Hollank (Hamburgische Schiffbau-Versuchsanstalt (Germany)), Andre Pittig (University of Göttingen), Reinhard Pietrowsky (Heinrich Heine University Düsseldorf)
Published
2026-01-31
OA status
hybrid
DOI
10.1159/000550820
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:6920137d7b814b8e,
  title = {Blended Cognitive Behavioral Therapy versus Standard Cognitive Behavioral Therapy for Unipolar Depression: A Multicenter Randomized Controlled Trial},
  author = {Jan Kalde and Ece Atik and Johannes Stricker and Magnus Schückes and Peter Neudeck and Pamela Abel and Johanna Hollank and Andre Pittig and Reinhard Pietrowsky},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1159/000550820},
  url = {https://doi.org/10.1159/000550820}
}

RIS

TY  - JOUR
TI  - Blended Cognitive Behavioral Therapy versus Standard Cognitive Behavioral Therapy for Unipolar Depression: A Multicenter Randomized Controlled Trial
AU  - Kalde, Jan
AU  - Atik, Ece
AU  - Stricker, Johannes
AU  - Schückes, Magnus
AU  - Neudeck, Peter
AU  - Abel, Pamela
AU  - Hollank, Johanna
AU  - Pittig, Andre
AU  - Pietrowsky, Reinhard
PY  - 2026
PB  - PubMed Central
DO  - 10.1159/000550820
UR  - https://doi.org/10.1159/000550820
ER  -

APA

Kalde, J., Atik, E., Stricker, J., Schückes, M., Neudeck, P., Abel, P., Hollank, J., Pittig, A., & Pietrowsky, R. (2026). Blended Cognitive Behavioral Therapy versus Standard Cognitive Behavioral Therapy for Unipolar Depression: A Multicenter Randomized Controlled Trial. PubMed Central. https://doi.org/10.1159/000550820

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