Effectiveness of a Novel Integrative Online Treatment for Depression (Deprexis): Randomized Controlled Trial
Overview
This randomized controlled trial evaluates Deprexis, an integrative web-based program combining behavioral activation, cognitive restructuring, mindfulness, and social skills training for depression. The study involved 396 German adults assigned to immediate or delayed access alongside usual care, measuring outcomes via the Beck Depression Inventory and Work and Social Adjustment Scale at post-treatment and six-month follow-up. Results indicate significant reductions in depression severity and improvements in social functioning, with effects maintained over time and reported as helpful by most users.
- ID
b7179498cb2a4f20- Source org
- PubMed Central
- Author
- Björn Meyer (GAIA (Germany)), Thomas Berger (University of Bern), Franz Caspar (University of Bern), Christopher G. Beevers (The University of Texas at Austin), Gerhard Andersson (Swedish Institute), Mario Weiss (GAIA (Germany))
- Published
- 2009-05-11
- OA status
- gold
- DOI
- 10.2196/jmir.1151
- PMID
- Not recorded
- PMCID
- Not recorded
- Citations
- 387
Tags
Verification
- identityok via crossref · score 1 · checked_at unknown
- legitimacykeep via unknown · score 1 · checked_at unknown
- linkok via http-check · 2026-07-21T15:52:31.592259+00:00
Cite this entry
BibTeX
@article{allodium:b7179498cb2a4f20,
title = {Effectiveness of a Novel Integrative Online Treatment for Depression (Deprexis): Randomized Controlled Trial},
author = {Björn Meyer and Thomas Berger and Franz Caspar and Christopher G. Beevers and Gerhard Andersson and Mario Weiss},
year = {2009},
journal = {PubMed Central},
doi = {10.2196/jmir.1151},
url = {https://doi.org/10.2196/jmir.1151}
}RIS
TY - JOUR TI - Effectiveness of a Novel Integrative Online Treatment for Depression (Deprexis): Randomized Controlled Trial AU - Meyer, Björn AU - Berger, Thomas AU - Caspar, Franz AU - Beevers, Christopher G. AU - Andersson, Gerhard AU - Weiss, Mario PY - 2009 PB - PubMed Central DO - 10.2196/jmir.1151 UR - https://doi.org/10.2196/jmir.1151 ER -
APA
Meyer, B., Berger, T., Caspar, F., Beevers, C. G., Andersson, G., & Weiss, M. (2009). Effectiveness of a Novel Integrative Online Treatment for Depression (Deprexis): Randomized Controlled Trial. PubMed Central. https://doi.org/10.2196/jmir.1151
Related entries
- Adherence to Established Treatment Guidelines Among Unguided Digital Interventions for Depression: Quality Evaluation of 28 Web-Based Programs and Mobile Apps
- Internet-Delivered Interpersonal Psychotherapy Versus Internet-Delivered Cognitive Behavioral Therapy for Adults With Depressive Symptoms: Randomized Controlled Noninferiority Trial
- Efficacy of a Cognitive Behavioral Therapy–Based Online Self-Help Group for Depression and Suicide Ideation: Randomized Controlled Trial
- Feasibility, efficacy, and perceptions of an online writing intervention in patients with depressive disorders: A randomized, multi-methods pilot study
- Cognitive and Behavioral Skills Exercises Completed by Patients with Major Depression During Smartphone Cognitive Behavioral Therapy: Secondary Analysis of a Randomized Controlled Trial
- Efficacy of Self-guided Internet-Based Cognitive Behavioral Therapy in the Treatment of Depressive Symptoms
- Protocol for a randomized trial to predict the efficacy of cognitive and behavioral interventions for symptoms of depression
- Brief Web-Based Intervention for Depression: Randomized Controlled Trial on Behavioral Activation
- Imagery rescripting and cognitive restructuring for inpatients with moderate and severe depression – a controlled pilot study
- Cognitive restructuring, behavioral activation and cognitive-behavioral therapy in the treatment of adult depression: A network meta-analysis.