DNA Repair Mechanisms
This cluster of papers focuses on the molecular mechanisms of the DNA damage response, including DNA repair pathways, genomic instability, the role of ATM and ATR kinases, homologous recombination, cell cycle checkpoints, and their implications in cancer biology. It also explores the involvement of histone H2AX and chromatin in maintaining genome stability.
Papers listed on taxonomy pages are the top few works per node from the OpenAlex snapshot. That list is not exhaustive and is not an endorsement. The topic map and the journal registry remain separate: there is still no authoritative topic-to-venue or topic-to-organization edge. Search is a lexical lookup, not a claim that a venue publishes a topic.
Most cited
- A simple salting out procedure for extracting DNA from human nucleated cells
- Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
- The DNA-damage response in human biology and disease
- The limited in vitro lifetime of human diploid cell strains
- Instability and decay of the primary structure of DNA
- Precise Measurement of the G+C Content of Deoxyribonucleic Acid by High-Performance Liquid Chromatography
Most recent
- Molecular basis of nick ligation in the nucleosome by DNA Ligase IIIα
- Audio long read: Could mending damaged DNA prolong life?
- The conformation of the complementary strand and the deformation of the DNA groove upon DDB2 binding justifies the different repair rates for cyclobutane pyrimidine dimers
- The Fanconi anemia pathway restrains MLL-rearranged leukemogenesis through suppressing non-homologous end joining-mediated genomic instability
- The1H, 15N and13C backbone resonance assignments of an intrinsically disordered region (124–270) of BRCA1 associated RING domain 1 (BARD1)
- AZD6738 (Ceralasertib) Enhances Trifluridine's Antitumor Effect in 5‐ FU –Resistant Colorectal Cancer Cells