Perioperative sleep optimisation and brain health in older adults (SLEEP-BOOST): protocol for a randomised controlled trial

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This protocol outlines a pilot randomized controlled trial investigating the feasibility and acceptability of a condensed Cognitive Behavioural Therapy for Insomnia (CBT-I) intervention in older adults undergoing elective orthopaedic surgery. The study aims to assess whether this preoperative sleep optimization strategy can improve insomnia severity and reduce postoperative neurocognitive disorders compared to sleep hygiene education. It is designed for researchers and clinicians interested in perioperative care protocols for older patients with insomnia.

ID
2670c21d9cac465a
Source org
PubMed Central
Author
Anaëlle E. Charles (Massachusetts General Hospital), Andrea A. Castillo Suárez (Massachusetts General Hospital), Mansi Chhajed (Massachusetts General Hospital), Mili Jimenez Gallardo (Massachusetts General Hospital), Karoline Sanchez Valdes (Massachusetts General Hospital), P H M Li (Harvard University), Hu K (Harvard University), Patricia Wong (Center for Pain and the Brain), John Winkelman (Massachusetts General Hospital), L Y Gao (Harvard University)
Published
2026-05-01
OA status
gold
DOI
10.1136/bmjopen-2026-116526
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:2670c21d9cac465a,
  title = {Perioperative sleep optimisation and brain health in older adults (SLEEP-BOOST): protocol for a randomised controlled trial},
  author = {Anaëlle E. Charles and Andrea A. Castillo Suárez and Mansi Chhajed and Mili Jimenez Gallardo and Karoline Sanchez Valdes and P H M Li and Hu K and Patricia Wong and John Winkelman and L Y Gao},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1136/bmjopen-2026-116526},
  url = {https://doi.org/10.1136/bmjopen-2026-116526}
}

RIS

TY  - JOUR
TI  - Perioperative sleep optimisation and brain health in older adults (SLEEP-BOOST): protocol for a randomised controlled trial
AU  - Charles, Anaëlle E.
AU  - Suárez, Andrea A. Castillo
AU  - Chhajed, Mansi
AU  - Gallardo, Mili Jimenez
AU  - Valdes, Karoline Sanchez
AU  - Li, P H M
AU  - K, Hu
AU  - Wong, Patricia
AU  - Winkelman, John
AU  - Gao, L Y
PY  - 2026
PB  - PubMed Central
DO  - 10.1136/bmjopen-2026-116526
UR  - https://doi.org/10.1136/bmjopen-2026-116526
ER  -

APA

Charles, A. E., Suárez, A. A. C., Chhajed, M., Gallardo, M. J., Valdes, K. S., Li, P. H. M., K, H., Wong, P., Winkelman, J., & Gao, L. Y. (2026). Perioperative sleep optimisation and brain health in older adults (SLEEP-BOOST): protocol for a randomised controlled trial. PubMed Central. https://doi.org/10.1136/bmjopen-2026-116526

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