Cognitive Behavioral Therapy and Tai Chi Reverse Cellular and Genomic Markers of Inflammation in Late-Life Insomnia: A Randomized Controlled Trial

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This randomized controlled trial investigates whether cognitive-behavioral therapy for insomnia (CBT-I) and Tai Chi Chih can reverse cellular and genomic markers of inflammation in older adults. The study compares these interventions against a sleep education control group, measuring outcomes such as C-reactive protein levels, cytokine production, and gene expression over several months. It is intended for researchers or clinicians interested in the physiological mechanisms linking insomnia treatment to inflammatory processes.

ID
64917896d359456f
Source org
OpenAlex
Author
Michael R. Irwin (University of California, Los Angeles), Richard Olmstead (Neurobehavioral Systems), Elizabeth C. Breen (Neurobehavioral Systems), Tuff Witarama, Carmen Carrillo, Nina Sadeghi, Jesusa M.G. Arevalo (University of California, Los Angeles), Jeffrey Ma (University of California, Los Angeles), Perry M. Nicassio (Neurobehavioral Systems), Richard R. Bootzin (University of Arizona), Steve W. Cole (University of California, Los Angeles)
Published
2015-02-04
OA status
gold
DOI
10.1016/j.biopsych.2015.01.010
PMID
Not recorded
PMCID
Not recorded
Citations
225

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BibTeX

@article{allodium:64917896d359456f,
  title = {Cognitive Behavioral Therapy and Tai Chi Reverse Cellular and Genomic Markers of Inflammation in Late-Life Insomnia: A Randomized Controlled Trial},
  author = {Michael R. Irwin and Richard Olmstead and Elizabeth C. Breen and Tuff Witarama and Carmen Carrillo and Nina Sadeghi and Jesusa M.G. Arevalo and Jeffrey Ma and Perry M. Nicassio and Richard R. Bootzin and Steve W. Cole},
  year = {2015},
  journal = {OpenAlex},
  doi = {10.1016/j.biopsych.2015.01.010},
  url = {https://doi.org/10.1016/j.biopsych.2015.01.010}
}

RIS

TY  - JOUR
TI  - Cognitive Behavioral Therapy and Tai Chi Reverse Cellular and Genomic Markers of Inflammation in Late-Life Insomnia: A Randomized Controlled Trial
AU  - Irwin, Michael R.
AU  - Olmstead, Richard
AU  - Breen, Elizabeth C.
AU  - Witarama, Tuff
AU  - Carrillo, Carmen
AU  - Sadeghi, Nina
AU  - Arevalo, Jesusa M.G.
AU  - Ma, Jeffrey
AU  - Nicassio, Perry M.
AU  - Bootzin, Richard R.
AU  - Cole, Steve W.
PY  - 2015
PB  - OpenAlex
DO  - 10.1016/j.biopsych.2015.01.010
UR  - https://doi.org/10.1016/j.biopsych.2015.01.010
ER  -

APA

Irwin, M. R., Olmstead, R., Breen, E. C., Witarama, T., Carrillo, C., Sadeghi, N., Arevalo, J. M., Ma, J., Nicassio, P. M., Bootzin, R. R., & Cole, S. W. (2015). Cognitive Behavioral Therapy and Tai Chi Reverse Cellular and Genomic Markers of Inflammation in Late-Life Insomnia: A Randomized Controlled Trial. OpenAlex. https://doi.org/10.1016/j.biopsych.2015.01.010

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