The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study

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This multicentric study investigates how Cognitive-Behavioral Therapy for Insomnia (CBT-I) affects cortical hyperarousal in patients with Chronic Insomnia Disorder, using quantitative EEG to measure the NREM delta/beta ratio. The research includes 98 participants across five centers who completed a 6-8-week CBT-I program, with assessments comparing pre- and post-treatment polysomnography data. Results indicate that CBT-I significantly increases the delta/beta ratio, suggesting reduced hyperarousal, with greater improvements observed in patients with short sleep duration compared to those with normal sleep duration.

ID
4aa4c91085fb49c0
Source org
PubMed Central
Author
Marco Sforza (Vita-Salute San Raffaele University), C. Morin (Université Laval), T. Dang-Vu (Institut Universitaire de Gériatrie de Montréal), Florence B. Pomares (Institut Universitaire de Gériatrie de Montréal), Aurore A. Perrault (Institut Universitaire de Gériatrie de Montréal), J. P. Gouin (Institut Universitaire de Gériatrie de Montréal), Jitka Bušková (Charles University), Karolína Janků (National Institute of Mental Health), Alexandros Vgontzas (Penn State Milton S. Hershey Medical Center), Julio Fernandez-Mendoza (Penn State Milton S. Hershey Medical Center), Célyne Bastien (Université Laval), Dieter Riemann (University of Freiburg), Chiara Baglioni (Marconi University), Giacomo Carollo (Vita-Salute San Raffaele University), Francesca Casoni (Vita-Salute San Raffaele University), M. Zucconi (Vita-Salute San Raffaele University), V. Castronovo (Vita-Salute San Raffaele University), Andrea Galbiati (Vita-Salute San Raffaele University), Luigi Ferini-Strambi (Vita-Salute San Raffaele University)
Published
2026-02-13
OA status
gold
DOI
10.1038/s41398-026-03882-1
PMID
Not recorded
PMCID
Not recorded
Citations
3

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BibTeX

@article{allodium:4aa4c91085fb49c0,
  title = {The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study},
  author = {Marco Sforza and C. Morin and T. Dang-Vu and Florence B. Pomares and Aurore A. Perrault and J. P. Gouin and Jitka Bušková and Karolína Janků and Alexandros Vgontzas and Julio Fernandez-Mendoza and Célyne Bastien and Dieter Riemann and Chiara Baglioni and Giacomo Carollo and Francesca Casoni and M. Zucconi and V. Castronovo and Andrea Galbiati and Luigi Ferini-Strambi},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1038/s41398-026-03882-1},
  url = {https://doi.org/10.1038/s41398-026-03882-1}
}

RIS

TY  - JOUR
TI  - The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study
AU  - Sforza, Marco
AU  - Morin, C.
AU  - Dang-Vu, T.
AU  - Pomares, Florence B.
AU  - Perrault, Aurore A.
AU  - Gouin, J. P.
AU  - Bušková, Jitka
AU  - Janků, Karolína
AU  - Vgontzas, Alexandros
AU  - Fernandez-Mendoza, Julio
AU  - Bastien, Célyne
AU  - Riemann, Dieter
AU  - Baglioni, Chiara
AU  - Carollo, Giacomo
AU  - Casoni, Francesca
AU  - Zucconi, M.
AU  - Castronovo, V.
AU  - Galbiati, Andrea
AU  - Ferini-Strambi, Luigi
PY  - 2026
PB  - PubMed Central
DO  - 10.1038/s41398-026-03882-1
UR  - https://doi.org/10.1038/s41398-026-03882-1
ER  -

APA

Sforza, M., Morin, C., Dang-Vu, T., Pomares, F. B., Perrault, A. A., Gouin, J. P., Bušková, J., Janků, K., Vgontzas, A., Fernandez-Mendoza, J., Bastien, C., Riemann, D., Baglioni, C., Carollo, G., Casoni, F., Zucconi, M., Castronovo, V., Galbiati, A., & Ferini-Strambi, L. (2026). The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study. PubMed Central. https://doi.org/10.1038/s41398-026-03882-1

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